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Which opioid is most likely to yield a false negative on standard immunoassay drug screens?
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Oxycodone, a commonly prescribed semi-synthetic opioid, is one of the opioids most likely to yield a false negative result on standard immunoassay drug screens. This is because many basic opioid immunoassays are designed to detect morphine and codeine, which have a different molecular structure than oxycodone. As a result, unless the test is specifically calibrated or includes an oxycodone-specific panel, the drug may go undetected despite being present in the sample. This limitation can have significant clinical, legal, and forensic implications, highlighting the importance of using targeted or confirmatory testing methods like GC-MS or LC-MS/MS to ensure accurate results.

\#Oxycodone #DrugTesting #FalseNegative #Immunoassay #ForensicToxicology #ClinicalToxicology #ForensicScience #ToxicologyFacts #DrugScreening #OpioidTesting #GCMS #LCMSMS #MadForensicScientist #ForensicEducation #ToxicologyTips
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Genre: Science & Technology
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RYD date created : 2025-08-12T06:31:48.300398Z
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