Just released! 10 points to consider when your stimulant stops working!
The answer is often - Move away from simply thinking about the stimulant!
New video! Key points covered:
1. What Are SNRIs and How Do They Work?
2. How Do SNRIs Affect Dopaminergic and Noradrenergic Pathways?
3. Why Are Desvenlafaxine and Duloxetine Effective for Severe Forms of Depression?
4. What Is the Role of Noradrenaline in Pain Management and Its Impact on SNRI Selection?
5. Why Is Venlafaxine Associated With Severe Withdrawal Symptoms?
The gut microbiome is often referred to as a superorganism due to the intricate symbiotic connections it maintains with the brain. These connections are evident through various pathways collectively known as the microbiota-gut-brain (MGB) axis.
Scientific evidence suggests that the administration of probiotics may have a positive impact on symptoms associated with Major Depressive Disorder (MDD) by enhancing serotonin availability and/or reducing the levels of inflammatory markers. Exploring the potential of probiotics as a novel treatment for MDD holds promise in revolutionizing antidepressant therapies, potentially mitigating the stigma, latency, and side effects commonly associated with conventional antidepressants.
For a more in-depth understanding of the relationship between the gut microbiome and depression pathophysiology, as well as the role of pre- and probiotics, you can refer to the detailed information available on the Psych Scene Hub:
psychscenehub.com/psychinsights/gut-microbiome-and…
For accredited learning head to The Academy:
www.academy.psychscene.com/
#clinicians #psychiatry #guthealth
Neurosteroids, also known as Neuroactive Steroids (NAS), constitute endogenous steroid hormones synthesized from cholesterol within the mitochondria of glial cells or derived from steroid hormone precursors such as progesterone, which accumulate within the nervous system. They exert localized and rapid effects on brain function and behavior.
These substances exert their influence on neuronal excitability either through direct transcriptional factor activity or via their non-genomic modulation of ion channels and cell receptors.
Noteworthy among neuroactive steroids are progesterone (PROG) and its reduced metabolite, Allopregnanolone (AlloP), which exhibit sedative-hypnotic, anxiolytic, anticonvulsant, and anti-stress properties through agonistic modulation of the GABA-A receptor.
For a more in-depth exploration of the mechanism of action of Allopregnanolone, refer to the Psych Scene Hub:
psychscenehub.com/psychinsights/neurosteroids-in-p…
And for accredited learning head to The Academy:
www.academy.psychscene.com/
Insomnia exhibits a close association with mental health conditions, underscoring the growing significance of comprehending circadian science and the determinants of the sleep-wake cycle. Notably, even a single night of complete sleep deprivation detrimentally influences the molecular clearance processes within the human brain, and the capacity for individuals to compensate for lost sleep is limited.
Sleep plays a pivotal role in restoring synaptic plasticity, fostering beneficial effects on learning processes. Conversely, sleep deprivation induces alterations in long-term potentiation (LTP) and long-term depression (LTD) mechanisms, heightens cortical excitability, and adversely impacts learning functions.
The repercussions of insomnia extend beyond mere sleep disturbance, profoundly affecting the quality of life through associated neuropsychiatric sequelae. These encompass impaired cognition, mood disturbances, and diminished overall functionality.
For a more in-depth exploration of the neurobiology, pathophysiology, assessment, and management of insomnia, refer to the resources available on the Psych Scene Hub:
psychscenehub.com/psychinsights/insomnia-assessmen…
And for accredited learning head to The Academy:
www.academy.psychscene.com/
#sleep #mentalhealth #psychiatry
The gut microbiome is often referred to as a superorganism due to the intricate symbiotic connections it maintains with the brain...
These connections are evident through various pathways collectively known as the microbiota-gut-brain (MGB) axis.
Scientific evidence suggests that the administration of probiotics may have a positive impact on symptoms associated with Major Depressive Disorder (MDD) by enhancing serotonin availability and/or reducing the levels of inflammatory markers.
Exploring the potential of probiotics as a novel treatment for MDD holds promise in revolutionizing antidepressant therapies, potentially mitigating the stigma, latency, and side effects commonly associated with conventional antidepressants.
For a more in-depth understanding of the relationship between the gut microbiome and depression pathophysiology, as well as the role of pre- and probiotics, you can refer to the detailed information available on The Hub:
psychscenehub.com/psychinsights/gut-microbiome-and…
And for accredited learning head to The Academy:
www.academy.psychscene.com/courses/psychopharmacol…
#guthealth #psychiatry #psychology
New video released!
🧠 Why is studying the effects of the environment on stress-related brain activity crucial? With the rise of urban living, we see a significant increase in mental disorders like anxiety, depression, and even psychosis. This is at least partly linked to heightened activity in the amygdala, the brain's fear centre, especially in city environments.
🌳 We'll explore how the amygdala, the anterior cingulate, and the prefrontal cortex form a key part of the limbic circuit involved in stress responses. You'll learn how nature can help reduce amygdala arousal and enhance our brain's ability to navigate anxieties, similar to mindfulness and meditation.
BDD, though not rare, proves profoundly distressing and debilitating. Detection and empathetic patient engagement are pivotal in a treatment plan that incorporates a halt to cosmetic procedures, psychological therapy, and targeted psychopharmacology.
In the general population, approximately 1 in 50 individuals may experience BDD, with estimates in cosmetic specialties surpassing seven to 10 times that figure. BDD patients often undergo multiple cosmetic procedures, none of which, by definition, offer enduring solutions.
For deeper insights into clinical features and management visit the Psych Scene Hub:
psychscenehub.com/psychinsights/body-dysmorphic-di…
And for accredited learning head to The Academy:
www.academy.psychscene.com/
#bdd #psychiatry #clinicians
📢 New Video Released! 🎥
🧠Join us on a captivating journey deep into the nuances of meditation and mindfulness - a double-edged sword.
In this video, we will better understand how these practices impact our brains and why different individuals may react differently to them.
This comprehensive guide explores the four brain functions implicated in meditation - attention regulation, bodily awareness, emotional regulation, and self-regulation. 🧠
We delve deeper into the effect of meditation and mindfulness practices on the different brain areas.
Discover practical tips for trying out meditation and mindfulness without falling into common pitfalls. If you're interested in understanding more about the neuroscientific aspects of meditation & mindfulness, you'll enjoy this video. ✅
📢 New Video Released! 🎥
In our latest video, we're going back to basics in the field of psychiatry and mental health. Join us as we shed light on a crucial aspect that often gets overlooked: brain neuroscience. 🧠
It's all too common to focus solely on diagnostic labels, but understanding the intricate workings of the brain is key to unlocking a deeper understanding of mental well-being. In this video, we'll take you on a fascinating journey through the brain's inner workings, revealing how it responds to challenges and circumstances. 💡
By exploring the neuroscience behind mental health, you'll gain valuable insights that can empower you to optimize your own mental well-being. Discover how the brain's remarkable adaptability can help you navigate and overcome various challenges, ultimately leading to a happier and healthier life. 🌟
The video has 4 parts:
Part 1: Understanding Brain Functionality
Part 2: Exploring the Different Brain Regions
Part3: Unveiling the Adaptive Nature of the Brain
Part 4: Unravelling the Consequences of Brain Dysfunction
Don't miss out on this enlightening exploration of the brain and its impact on mental well-being.
Dr Sanil Rege is a Consultant Psychiatrist, and this channel covers all things Psychiatry, Neuroscience and Mental health-related.
As an academic lead for Psych Scene, he has provided training to over 10,000 mental health professionals over the years.
He founded Psych Scene because he saw a need for comprehensive, world-class training that would boost careers and improve patient care.
We aim to create videos that improve the understanding of mental illness globally.
Whether you are a doctor, psychiatrist, medical student, psychiatry trainee, nurse, psychologist, social worker or someone who is interested in mental health - This channel will give you a comprehensive and practical overview of mental health disorders.