https://www.cdc.gov/nontuberculous-mycobacteria/about/index.html
Overview. Nontuberculous mycobacteria (NTM) are bacteria (germs) found in soil, dust and water. NTM do not include M. tuberculosis (the cause of tuberculosis) or M. leprae (the cause of Hansen's disease ). Anyone can get an NTM infection but people with underlying lung disease or weakened immune systems are at increased risk.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8135042/
Non-tuberculous mycobacteria (NTM) is a collective name given to a group of more than 190 species of Mycobacterium other than Mycobacterium tuberculosis and Mycobacterium leprae. These organisms are ubiquitous in the environment, in particular in soil and water sources, and are increasingly recognized as a cause of human disease. Non

https://my.clevelandclinic.org/health/diseases/21200-nontuberculous-mycobacteria-infections
Nontuberculous Mycobacteria Infections. Nontuberculous mycobacteria (NTM) infections are wounds or illnesses caused by Mycobacterium bacteria, except for those that cause tuberculosis and leprosy (Hansen's disease). NTM can infect your lungs, skin, bones, lymph nodes or many organs in your body. M. avium complex (MAC) is the most common cause.

https://www.idsociety.org/practice-guideline/nontuberculous-mycobacterial-ntm-diseases/
Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of which can produce disease in humans of all ages and can affect both pulmonary and extrapulmonary sites. This guideline focuses on pulmonary disease in adults (without cystic fibrosis or human immunodeficiency virus infection) caused by the most common NTM pathogens such as Mycobacterium avium complex

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881820/
Introduction. Non-tuberculous mycobacteria (NTM) are known by several names including environmental mycobacteria, atypical mycobacteria or anonymous mycobacteria, mycobacteria other than Mycobacterium tuberculosis (Mtb) (MOTT) and its close relatives, M. africanum, M. bovis, M. canetti, M. caprae, M. pinnipedii and M. leprae 1.These organisms are ubiquitous in the environment and have been

https://www.ncbi.nlm.nih.gov/books/NBK551583/
Etiology. Following the discovery of Mycobacterium tuberculosis by Robert Koch in 1882, nontuberculous mycobacteria (NTM) have gradually been identified and categorized. The first of these, Mycobacterium avium, was first identified in birds and differentiated from tuberculosis by 1890. Further NTM were gradually identified over the years; however, they were not recognized as responsible for

https://en.wikipedia.org/wiki/Nontuberculous_mycobacteria
Nontuberculous mycobacteria (NTM), also known as environmental mycobacteria, atypical mycobacteria and mycobacteria other than tuberculosis (MOTT), are mycobacteria which do not cause tuberculosis or leprosy/Hansen's disease.NTM are able to cause pulmonary diseases that resemble tuberculosis. Mycobacteriosis is any of these illnesses, usually meant to exclude tuberculosis.

https://www.nature.com/articles/s41579-020-0331-1
Non-tuberculous mycobacteria, such as Mycobacterium abscessus, are an increasing global health burden, in part due their extensive drug resistance. In this Review, Johansen, Herrmann and Kremer

https://www.lung.org/lung-health-diseases/lung-disease-lookup/nontuberculous-mycobacteria/learn-about-nontuberculosis-mycobacteria
Nontuberculous mycobacteria are a group of bacteria naturally found in soil, water and dust worldwide. Everyone inhales NTM into their lungs as part of daily life, and in most people the organisms do no harm. But in a small number of vulnerable individuals, NTM gets established in the lungs as an infection.

https://journal.chestnet.org/article/S0012-3692(21)04084-8/fulltext
Nontuberculous mycobacteria (NTM) encompass all mycobacterial species excluding those that comprise Mycobacterium tuberculosis complex and Mycobacterium leprae. NTM are ubiquitous environmental organisms commonly found in water and soil. In humans, the most frequent site of infection is the lungs.

https://www.atsjournals.org/doi/full/10.1164/rccm.200604-571ST
The first clue to the identity of a nontuberculous mycobacterium, after a negative result for M. tuberculosis from a nucleic acid amplification test, is frequently the rate of growth of the NTM isolate, especially if there is rapid growth. Because the RGM are frequently isolated under similar clinical circumstances, members of this group of

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00586-7/fulltext
The 2020 clinical practice guideline for the treatment of non-tuberculous mycobacterial pulmonary disease (NTM-PD) by the American Thoracic Society, European Respiratory Society, European Society of Clinical Microbiology and Infectious Diseases, and Infectious Diseases Society of America; and the 2017 management guideline by the British Thoracic Society covered pulmonary diseases in adults

https://www.brighamandwomens.org/lung-center/diseases-and-conditions/tuberculosis-and-nontuberculosis-mycobacteria
To request an appointment, please call 1-844-294-5864 or fill out an online appointment request form. To refer a patient, please call 1-800-MD-TO-BWH (1-800-638-6294) or see our list of referral options. Tuberculosis (TB) is a chronic bacterial disease infecting the lungs, kidneys, spine and/or brain. TB is an airborne mycobacterium that can be

https://radiopaedia.org/articles/pulmonary-non-tuberculous-mycobacterial-infection-3
Citation, DOI, disclosures and article data. Pulmonary non-tuberculous mycobacterial (NTM) infection refers to pulmonary infection caused by one of the large number (at least 150) mycobacterial species other than Mycobacterium tuberculosis. However, certain species are much more common than others.

https://www.uptodate.com/contents/overview-of-nontuberculous-mycobacterial-infections
In broad terms, nontuberculous mycobacteria (NTM) can cause four clinical syndromes in humans [ 2,3 ]: Pulmonary disease - This especially occurs in individuals with underlying lung disease and in patients with cystic fibrosis [ 4 ]. It can also occur in individuals without previously known lung disease. Mycobacterium avium complex (MAC

https://pubmed.ncbi.nlm.nih.gov/27826888/
Non-tuberculous mycobacteria (NTM) are species other than those belonging to the Mycobacterium tuberculosis complex and do not cause leprosy. NTM are generally free-living organisms that are ubiquitous in the environment. There have been more than 140 NTM species identified to-date. They can cause a wide range of infections, with pulmonary

https://thorax.bmj.com/content/72/Suppl_2/ii1
Background. Since the publication of the British Thoracic Society (BTS) Guideline on the 'Management of opportunistic mycobacterial infections' in 2000, our understanding of the epidemiology, microbiology and management of non-tuberculous mycobacterial-pulmonary disease (NTM-PD) has advanced.3 The incidence and prevalence of NTM-PD are increasing and are most likely explained by improved

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297667/
Pulmonary diseases due to mycobacteria cause significant morbidity and mortality to human health. In addition to tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), recent epidemiological studies have shown the emergence of non-tuberculous mycobacteria (NTM) species in causing lung diseases in humans. Although more than 170 NTM species are present in various environmental niches

https://www.msdmanuals.com/professional/infectious-diseases/mycobacteria/nontuberculous-mycobacterial-infections
Mycobacteria other than Mycobacterium tuberculosis can be human pathogens, and the incidence of infection appears to be increasing. These organisms are commonly present in soil and water and are much less virulent for humans than M. tuberculosis. Infections caused by these organisms have been called atypical, environmental, and nontuberculous

https://www.sciencedirect.com/science/article/pii/S2405579421000334
Non-tuberculous mycobacteria (NTM) is a collective name given to a group of more than 190 species of Mycobacterium other than Mycobacterium tuberculosis and Mycobacterium leprae [1]. These organisms are ubiquitous in the environment, in particular in soil and water sources, and are increasingly recognized as a cause of human disease. Non

https://www.healthline.com/health/non-tuberculosis-mycobacterium
chronic cough with mucus and, later, blood. fatigue. weight loss. night sweats. loss of appetite. shortness of breath. chest pain. recurring respiratory infections. Seek emergency medical care if

https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.00303/full
Non-tuberculous mycobacteria (NTM) are ubiquitous, free living, environmental saprophytic organisms known to occupy water systems, soil, and vegetation. Belonging to the genus Mycobacterium (which include Mycobacterium tuberculosis (TB) and Mycobacterium leprae ), there are over 170 identified NTM species with new species discoveries increasing

https://www.unmc.edu/intmed/divisions/id/ntm/clinic.html
Assistant Professor, Division of Infectious Diseases Medical Director, Employee Health Director, Community Infectious Diseases Service. Phone: 402-559-8650 Fax: 402-559-5581

https://journals.asm.org/doi/abs/10.1128/spectrum.00199-24?af=R
Rapidly growing mycobacteria (RGM), a category within nontuberculous mycobacteria (NTM), are prevalent in various environments and can lead to infections in humans. The rise of antimicrobial resistance within RGM is a documented concern. ... Johansen MD, Herrmann JL, Kremer L. 2020. Non-tuberculous mycobacteria and the rise of Mycobacterium

https://erj.ersjournals.com/content/56/1/2000535
Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of which can produce disease in humans of all ages and can affect both pulmonary and extrapulmonary sites. This guideline focuses on pulmonary disease in adults (without cystic fibrosis or human immunodeficiency virus infection) caused by the most common NTM pathogens such as Mycobacterium avium complex

https://www.semanticscholar.org/paper/Mycobacterium-gordoniasis-of-the-cervical-lymph-A-Peng-Ma/df3ad0dad3ae3f3c3cb969c2fa6648a7b4b4f757
This case report and the clinical epidemiological research on improving NTM have important guiding significance for improving decision-making in clinical treatments. BACKGROUND Owing to the advancement in bacterial identification techniques, the detection rate of non-tuberculous mycobacterium (NTM) has been on the rise. Different from Mycobacterium tuberculosis , the clinical symptoms of NTM

https://pubmed.ncbi.nlm.nih.gov/38930534/
The Esx-1 family proteins of the Type VII secretion systems of Mycobacterium bovis and Mycobacterium tuberculosis have been assessed and are frequently used as candidates for tuberculosis (TB) diagnosis in both humans and animals. The presence of ESAT-6 and CFP 10 proteins, which are the most immunogenic proteins of the Esx-1 system and have been widely investigated for the immunodiagnosis of

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4871867
This study detected 7.69% non-tuberculous mycobacteria (NTM) by RT-PCR. All NTM positive samples were negative by TB-LAMP. TB-LAMP is easy to perform, cost effective assay which provides very reliable results with high sensitivity and specificity. World Health Organization recommended TB-LAMP assay as a rapid molecular diagnostic test for rapid

https://www.mdpi.com/1420-3049/29/13/3076
Tuberculosis is a serious public health problem worldwide. The search for new antibiotics has become a priority, especially with the emergence of resistant strains. A new family of imidazoquinoline derivatives, structurally analogous to triazolophthalazines, which had previously shown good antituberculosis activity, were designed to inhibit InhA, an essential enzyme for Mycobacterium

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995077/
The incidence of infections by rapidly growing mycobacteria has increased in recent decades. nontuberculous mycobacteria(NTM) represent over 190 species and subspecies and can cause both pulmonary and extrapulmonary symptoms.The Mycobacterium abscessus complex (MABC)is among the most drug-resistant mycobacterial species, and prompt diagnosis and effective eradication are burdensome.