https://www.youtube.com/watch?v=Lcf9o26ET8s
ChocSoulBrutha is hilarious and should have his own channel if he doesn't already!

https://www.breastcancer.org/treatment/targeted-therapy/kadcyla
Learn more. Kadcyla (T-DM1) is a targeted therapy used to treat HER2-positive metastatic breast cancer. Learn more about Kadcyla.

https://breastcancernow.org/about-breast-cancer/treatment/targeted-biological-therapy/trastuzumab-emtansine-kadcyla/
Trastuzumab emtansine is a targeted therapy. Targeted therapy is the name given to a group of drugs that block the growth and spread of cancer. They target and interfere with processes in the cells that help cancer grow. Trastuzumab emtansine is the drug's non-branded name. You may hear it called Kadcyla, its brand name, or TDM1, its chemical

https://www.elprocus.com/time-division-multiplexing/
Time-division multiplexing method works by putting several data streams within a single signal by dividing the signal into various segments, where each segment has a very short duration. Every individual data stream at the receiving end is reassembled depending on the timing. In the following TDM diagram, when the three sources A, B & C wants

https://journals.lww.com/jcge/Fulltext/2021/03000/Therapeutic_Drug_Monitoring_for_Current_and.4.aspx
biologic agents targeting tumor necrosis factor, α4β7 integrin or interleukins 12 and 23; and Janus kinase inhibitors. TDM is recommended to guide treatment decisions for some of these agents. Published literature concerning TDM for IBD treatments was reviewed. S.D.L., R.S., and E.V.L. drew on their clinical experiences. Polymorphisms resulting in altered enzymatic activity inactivating

https://gastro.org/clinical-guidance/therapeutic-drug-monitoring-in-inflammatory-bowel-disease-ibd/
A guide to successfully implementing therapeutic drug monitoring (TDM) with anti-tumor necrosis factor (TNF)-α agents and thiopurines for patients with inflammatory bowel disease (IBD). Published August 3, 2017 Joseph D. Feuerstein, Geoffrey C. Nguyen, Sonia S. Kupfer, Yngve Falck-Ytter, Siddharth Singh on behalf of the AGA Institute Clinical

https://www.drugs.com/medical-answers/tdm1-chemotherapy-3562468/
Official answer. by Drugs.com. T-DM1 chemotherapy refers to treatment with Kadcyla, which is a targeted treatment that may be used to treat HER2-positive breast cancer in women who meet certain criteria. The chemical name for Kadcyla is T-DM1 (also called ado-trastuzumab emtansine) and it is a combination of two medicines: trastuzumab which is

https://www.geeksforgeeks.org/frequency-division-and-time-division-multiplexing/
2. Time Division Multiplexing (TDM): This happens when the data transmission rate of media is greater than that of the source, and each signal is allotted a definite amount of time. These slots are so small that all transmissions appear to be parallel. In frequency division multiplexing all the signals operate at the same time with different

https://www.cancernetwork.com/view/fda-approves-t-dm1-kadcyla-her2-positive-breast-cancer
The US Food and Drug Administration (FDA) approved ado-trastuzumab emtansine (Kadcyla) for the treatment of patients with metastatic HER2-positive breast cancer earlier today. HER2-positive disease accounts for nearly 20% of all breast cancers. The new drug, known as T-DM1 during clinical research, is intended for patients whose disease has

https://electronicscoach.com/time-division-multiplexing.html
For a TDM signal pulse per second is the signalling rate denoted as 'r'. Thus, Implementation of TDM. The technique of time division multiplexing can be implemented in basically two ways: 1. Synchronous TDM: In this technique, the time slots are assigned at the beginning, irrespective of the idea about the presence of data at the source

https://ashpublications.org/blood/article/138/Supplement%201/3498/479670/Disease-Kinetics-Measured-By-Circulating-Tumor-DNA
Background Currently available clinical and biological prognostic factors do not adequately identify first-line DLBCL patients at risk for treatment failure. In DLBCL, circulating tumor DNA (ctDNA) can be utilized as a for molecular disease classification, detect minimal residual disease (MRD) or predict disease progression.

https://sourceforge.net/projects/tdm-gcc/files/TDM-GCC%20Old%20Releases/TDM-GCC%204.8%20series/
Top Rated Business VoIP Provider for 2024 for as low as $20/mo*! Message, video, and phone on any device. Trusted by over 400,000 businesses. - Includes 100+ Premium Features. - Unlimited Calling, Faxing, SMS, Conferencing. Get Quote. GCC for 32-bit and 64-bit Windows with a real installer & updater.

https://www.uptodate.com/contents/clinical-presentation-and-management-of-thymoma-and-thymic-carcinoma
INTRODUCTION. Thymic tumors are rare neoplasms that arise in the anterior mediastinum. The clinical presentation, diagnosis, staging, and management of thymoma and thymic carcinoma are reviewed here. The pathology of thymic carcinomas, the initial approach to patients with an anterior mediastinal mass, and the diagnosis and management of thymic

https://networkencyclopedia.com/time-division-multiple-access-tdma/
4. Differences Between TDMA and TDM. While TDMA (Time Division Multiple Access) and TDM (Time Division Multiplexing) share a common principle of time-based division of channels, their application and context of use differ significantly. TDM is a broader concept used in various forms of communication, including wired networks, where multiple

https://www.tdmx.eu/.cm4all/uproc.php/0/TDMx_Reference.pdf?_=15fa5730ef0&cdp=a
suitable for teaching TDM in undergraduate studies. TDMx was developed using reactive programming with a server-client architecture: TDMx reactively visualises your input such as dosing history, patient covariates or drug measurements. Thereby, TDMx provides quick answers to clinically relevant questions.

https://www.hematologyandoncology.net/archives/january-2014/update-on-the-diagnosis-and-management-of-thalassemia/
MW In adults, hemoglobin is a 4-subunit protein (tetramer) made up of 2 copies each of 2 different subunits, α-globin and β-globin. Mutations in the genes that encode these proteins cause 2 major classes of thalassemia, α -thalassemia and β -thalassemia. Clinically, these disorders cause a spectrum of disease that varies in severity

https://badgut.org/information-centre/a-z-digestive-topics/therapeutic-drug-monitoring/
The goal of therapeutic drug monitoring is to maximize the clinical benefit of a medication while minimizing its side effects.

https://www.scribd.com/document/634386867/Implementation-complexity-problem-set
Implementation complexity problem set - Free download as Word Doc (.doc / .docx), PDF File (.pdf), Text File (.txt) or read online for free. 1. The implementation complexity of the 120-line TDM switch is 14,976 with a single-stage space matrix. 2. The complexity is reduced to 13,900 when groups of 4 inputs are combined into higher-level signals, forming 30 inputs with 96 channels each.

https://www.chegg.com/homework-help/data-communications-and-networking-5th-edition-chapter-6-problem-8p-solution-9780073376226
8P. Step-by-step solution. Step 1 of 4. Given: There are four channels. • Two with a bit rate of 200 kbps. • Two with a bit rate of 150 kbps. • It is multiplexed using slot TDM with no synchronization bits. Here, allocate the frame carries four bits from each of the first two channels and allocate another frame carries three bits from

https://www.jcehepatology.com/article/S0973-6883(21)00239-5/pdf
Diagnosis and management of tuberculosis (TB) in patients with cirrhosis remains challenging. We studied the clinical spectrum, diagnosis, and management of TB along with the assessment of the diagnostic util-ity of various laboratory investigations in this cohort. Methods: A retrospective review of records of patients with cirrhosis (July 2017

https://www.ktunotes.in/wp-content/uploads/2018/05/DC-M4-Ktunotes.in_.pdf
TDM is a digital multiplexing technique for combining several low-rate channels into one high-rate one. Time Slots and Frames In synchronous TDM, the data flow of each input connection is divided into units, where each input occupies one input time slot. A unit can be 1 bit, one character, or one block of data.

https://www.merckmanuals.com/professional/immunology-allergic-disorders/immunodeficiency-disorders/chronic-granulomatous-disease-cgd
Flow cytometric oxidative (respiratory) burst assay. Diagnosis of chronic granulomatous disease is by a flow cytometric oxidative (respiratory) burst assay to detect oxygen radical production using dihydrorhodamine 123 (DHR) or nitroblue tetrazolium (NBT).

https://www.merckmanuals.com/professional/hematology-and-oncology/anemias-caused-by-hemolysis/thalassemias
Thalassemias are a group of inherited microcytic, hemolytic anemias characterized by defective hemoglobin synthesis. Alpha-thalassemia is particularly common among people with African, Mediterranean, or Southeast Asian ancestry. Beta-thalassemia is more common among people with Mediterranean, Middle Eastern, Southeast Asian, or Indian ancestry.