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Multiple myeloma: 2024 update on diagnosis, risk ... - PubMed

https://pubmed.ncbi.nlm.nih.gov/38943315/
Disease overview: Multiple myeloma accounts for approximately 10% of hematologic malignancies. Diagnosis: The diagnosis requires ≥10% clonal bone marrow plasma cells or a biopsy proven plasmacytoma plus evidence of one or more multiple myeloma defining events (MDE): CRAB (hypercalcemia, renal failure, anemia, or lytic bone lesions) attributable to the plasma cell disorder, bone marrow clonal

Multiple myeloma | Nature Reviews Disease Primers

https://www.nature.com/articles/s41572-024-00529-7
Multiple myeloma is a haematological lymphoid malignancy involving tumoural plasma cells. In this Primer, Malard et al. discuss the epidemiology, mechanisms, diagnosis and treatments for multiple

The Challenging Approach to Multiple Myeloma: From Disease Diagnosis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11202048/
1. Introduction. In patients with multiple myeloma (MM), accounting for 10% of all hematological malignancies, the clinical features of the disease and the potential complications caused from therapies require close collaboration between hematologists and different specialists, starting with laboratory assistants, nephrologists, radiologists, neurologists, sometimes neurosurgeons and others.

Multiple Myeloma Patients in Desperate Need of More Effective ... - MSN

https://www.msn.com/en-us/health/other/multiple-myeloma-patients-in-desperate-need-of-more-effective-treatment-find-hope-in-cancer-drug-designed-to-recognize-and-kill-cancer-cells/ar-BB1oWGxL
A t this year's American Society of Clinical Oncology (ASCO) conference, one of the largest gatherings of leaders in cancer research, SurvivorNet had the opportunity to speak to influential

Multiple Myeloma in People of Working Age: A Systematic Review and

https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/6292479
multiple myeloma, work d e research. 2.4.ySelection. gloferesults, fours(TS,,,d)yscreened ... relationship n work d myeloma. Cancer's impact onemploymentsagliteratureg>nancial,frome,traveltots ... tients d with peripheral d stem cell transplant,"

FDA Approves Oncopeptides´ PEPAXTO® (melphalan flufenamide) for

https://www.prnewswire.com/news-releases/fda-approves-oncopeptides-pepaxto-melphalan-flufenamide-for-patients-with-triple-class-refractory-multiple-myeloma-301237310.html
Multiple myeloma is a cancer of plasma cells, a type of white blood cell which produces antibodies to help fight infection. Multiple myeloma causes cancer cells to accumulate in the bone marrow.

Multiple myeloma and stem cell transplant | Mayo Clinic Connect

https://connect.mayoclinic.org/discussion/multiple-myeloma-and-stem-cell-transplant/
Multiple myeloma and stem cell transplant Posted by rprice0519 @rprice0519 , 5 hours ago Do all multiple myeloma patients check to see if they are a candidate for stem cell transplant?

Targeted Cancer Drugs Keep Myeloma Patients Up And Running

https://www.npr.org/sections/health-shots/2013/02/18/172098789/targeted-cancer-drugs-keep-myeloma-patients-up-and-running
Pomalyst is the latest of a half-dozen myeloma drugs developed in the decade or so since Wright got diagnosed. Another, called Kyprolis, won FDA approval last summer. Like many so-called "targeted

Can Immunotherapy For Cancer Go Mainstream? : Shots - NPR

https://www.npr.org/sections/health-shots/2016/09/17/494230963/cancer-immunotherapy-at-a-crossroads
The immunotherapy drug Yervoy, also from Bristol-Myers, is priced at $157.46 per milligram. "To put that into perspective, that's approximately 4,000 times the cost of gold," Dr. Leonard Saltz, of

Beat AML Master Trial: A Groundbreaking Clinical Trial for Acute

https://www.lls.org/sites/default/files/national/Revised%20Beat%20AML%20Toolkit%20About%20Master%20Clinical%20Trial.pdf
clinical research organization and a single genomic provider. The protocol is designed to facilitate a collaborative, fast-acting clinical trial consortium that represents an attractive venue for testing new agents moving forward. This Master Trial has the potential to stand as a model for future cancer clinical trials.

New cancer treatments may be on the horizon—thanks to mRNA vaccines

https://www.nationalgeographic.com/science/article/new-cancer-treatments-may-be-on-the-horizonthanks-to-mrna-vaccines
In a study in a 2018 issue of the journal Molecular Therapy, researchers constructed an mRNA vaccine to be combined with a monoclonal antibody (a synthetic antibody made in the lab) to enhance the

COVID-19 Vaccines in People with Cancer

https://www.cancer.org/cancer/managing-cancer/coronavirus-covid-19-and-cancer/covid-19-vaccines-in-people-with-cancer.html
COVID-19, caused by the SARS-CoV-2 virus, continues to have an impact on many people, including people with cancer, their families, and caregivers.(To learn more about COVID-19 and how it might affect people with cancer and their caregivers, see Questions About COVID-19 and Cancer.). Vaccines (also called immunizations or vaccinations) are available to help protect against COVID-19.

What Are Second Cancers? | American Cancer Society

https://www.cancer.org/cancer/survivorship/long-term-health-concerns/second-cancers-in-adults/what-are-second-cancers.html
This is called a second cancer. A second cancer is a new cancer that's unrelated to any previous cancer diagnosis. It's a completely different type of cancer. Sometimes the new cancer is in the same organ or area of the body as the first cancer. For example, someone who was treated for a certain type of colorectal cancer can get another type of

DNA sequencing improves cancer treatment but remains underused. Why?

https://www.usatoday.com/story/news/health/2023/06/06/dna-sequencing-cancer-treatment-underused-explained/70272960007/
Why sequence a tumor. In some cases, therapies are available based on genetic mutations in the tumor itself. Cancer starts with normal cells that transform through random mutations into rapidly

Study: Genetics can explain why sex matters in some cancer outcomes.

https://www.usatoday.com/story/news/health/2023/06/21/study-genetics-can-explain-why-sex-matters-in-some-cancer-outcomes/70340015007/
New studies confirm: sex matters. A pair of studies shows the Y chromosome, which characterizes males, plays a key role in colon and bladder cancers. It's long been known men fare worse with colon

Men Lose Y Chromosomes as They Age - The Atlantic

https://www.theatlantic.com/science/archive/2019/12/men-lose-y-chromosomes-cells-they-age/603013/
Studies have linked loss of the Y chromosome in blood to cancer, heart disease, and other disorders. Now a new study—the largest yet of this phenomenon—estimates that 20 percent of 205,011 men

Clinical Trials: What You Need to Know - American Cancer Society

https://www.cancer.org/cancer/managing-cancer/making-treatment-decisions/clinical-trials/what-you-need-to-know.html
Help us end cancer as we know it, for everyone. Knowing all you can about clinical trials can help you feel better when deciding whether or not to take part in one. This guide addresses many basic questions and concerns about clinical trials so that you will be better prepared to discuss this option with your doctor and your family. It can help

Nuts For Longevity: Daily Handful Is Linked To Longer Life

https://www.npr.org/sections/thesalt/2013/11/21/246549388/nuts-for-longevity-daily-handful-is-linked-to-longer-life
Email. Men and women who were regularly munching on peanuts or tree nuts in their 30s and 40s were significantly more likely to reach their 70s, a study found. Researchers say they aren't sure why

Finding Risks, Not Answers, in Gene Tests - The New York Times

https://www.nytimes.com/2014/09/23/health/finding-risks-not-answers-in-gene-tests.html
Sept. 26, 2014. An article on Tuesday about genetic testing for cancer risk referred incorrectly at one point to the role that the genes BRCA1 and BRCA2 play in breast cancer. As the article

Effects of Diet and Physical Activity on Risks for Certain Cancers

https://www.cancer.org/cancer/risk-prevention/diet-physical-activity/acs-guidelines-nutrition-physical-activity-cancer-prevention/diet-and-activity.html
Diets higher in calcium and calcium-rich dairy may reduce risk. Alcohol use increases the risk for both pre- and post-menopausal breast cancer. Colorectal. Excess body weight is a strong risk factor. Regular moderate to vigorous physical activity can reduce risk of colon, but not rectal, cancer.

Does Vitamin D Really Protect Against Colorectal Cancer?

https://www.npr.org/sections/health-shots/2018/06/14/619896924/does-vitamin-d-really-protect-against-colorectal-cancer
People who had higher circulating blood levels of vitamin D, above the range deemed "sufficient," had a 22 percent lower risk, she says. The study pooled findings from 17 previous studies that

Coping with Cancer Recurrence | Treating Cancer Recurrence

https://www.cancer.org/cancer/survivorship/long-term-health-concerns/recurrence/coping-with-cancer-recurrence.html
Coping with Cancer Recurrence. If cancer comes back it can be shocking for you and the people closest to you. The medical work-up is difficult and all of the emotions you had when you were first diagnosed can return - and might be even stronger this time. You might feel more cautious, guarded, and less hopeful than ever before.

Atul Gawande's 'Checklist' For Surgery Success : NPR

https://www.npr.org/2010/01/05/122226184/atul-gawandes-checklist-for-surgery-success
Atul Gawande is a staff member of Brigham and Women's Hospital and the Dana Farber Cancer Institute. His other books include Better and Complications. Fred Field hide caption