https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085555/
Abstract. Hirudin, an acidic polypeptide secreted by the salivary glands of Hirudo medicinalis (also known as "Shuizhi" in traditional Chinese medicine), is the strongest natural specific inhibitor of thrombin found so far. Hirudin has been demonstrated to possess potent anti-thrombotic effect in previous studies.

https://www.medscape.com/viewarticle/463459
Abstract and Introduction. The clinical utility of subcutaneous hirudins is discussed. The term "hirudins" refers to a class of antithrombotic agents structurally derived from the medicinal leech

https://medical-dictionary.thefreedictionary.com/hirudin
hirudin: [ hĭ-roo´din ] the active principle of the buccal secretion of leeches; it prevents clotting of the blood. A product made with recombinant technology is used as an anticoagulant .

https://pubmed.ncbi.nlm.nih.gov/10603506/
It is hoped that these initial results can be confirmed and that hirudin can be proved to be a safe and effective treatment for thrombotic syndromes of the venous and arterial circulatory systems. Over a century has passed since the anticoagulant properties of hirudin were identified. Our understanding of this unique and promising 65 amino acid

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847633/
Background: To investigate the efficacy and safety of hirudin plus aspirin therapy compared with warfarin in the secondary prevention of cardioembolic stroke due to nonvalvular atrial fibrillation (NVAF). Methods: Patients with cardioembolic stroke due to NVAF were prospectively enrolled from 18 collaborating hospitals from Dec 2011 to June 2015. . Fourteen days after stroke onset, eligible

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10935440/
Furthermore, hirudin has been used in cellular or animal models of CKD for different types of research. The results suggest that hirudin may have preventive effects in vitro or in vivo, offering a potential treatment for the disease. This article systematically reviews the role and beneficial effects of hirudin in CKD.

https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/hirudin
Hirudin is a naturally occurring inhibitor of thrombin that is a single-chain polypeptide of 65 amino acid residues with an apparent molecular weight of 7 kDa. The structure is stabilized by three intramolecular disulfide bridges. In 1986, recombinant hirudin (r-hirudin) became available. Desirudin ([Val 1, Val 2]-63-desulfohirudin) and lepirudin ([Leu 12]-63-desulfohirudin) are

https://en.wikipedia.org/wiki/Hirudin
Hirudin is a naturally occurring peptide in the salivary glands of blood-sucking leeches (such as Hirudo medicinalis) that has a blood anticoagulant property. This is essential for the leeches' habit of feeding on blood, since it keeps a host's blood flowing after the worm's initial puncture of the skin.. Hirudin (MEROPS I14.001) belongs to a superfamily (MEROPS IM) of protease inhibitors that

https://journals.sagepub.com/doi/10.1177/106002809202601211
Hirudin has demonstrated potent anticoagulant effects. Although hirudin could have a significant impact on the therapeutic management of patients requiring anticoagulant therapy, only a limited number of human studies have been published to date. Trials comparing hirudin and heparin in specific patient populations are still ongoing.

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1527-3466.1992.tb00247.x
Hirudin: The Promising Antithrombotic Fritz Markwardt Institute of Pharmacology and Toxicology, Medical Academy Erfurt, Erfurt, Germany Key Words: Hirudin-Antithrombotic-Reclinical and clinical studies. It has long been known that medicinal leeches (Hirudo medicinalis) contain a substance with anticoagulant properties.

https://www.picmonic.com/pathways/medical-terminology/courses/standard/medical-terminology-2411/pathogen-terms-12643/hirudi-or-hirudini_5123
Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores. Learn Hirud/i or Hirudin/i - Pathogen Terms - Medical Terminology for Medical Terminology faster and easier with Picmonic's unforgettable videos, stories, and quizzes! Picmonic is research proven to increase your memory

https://pubmed.ncbi.nlm.nih.gov/11863317/
The aim of this double-blind, placebo-controlled clinical trial was to evaluate the efficacy and safety of a Hirudin-containing cream (Hirudex cream; Hirudo medicinalis extract 280 UI/100 g) in patients affected with bruises with or without hematoma. 60 men and women between the ages of 18 and 65 years with a unilateral acute musculoskeletal

https://www.youtube.com/watch?v=CXzkIzWWwGI
What does Hirudin Therapy mean in English?

https://pubmed.ncbi.nlm.nih.gov/8328213/
Hirudin is in particular effective in the inhibition of the feedback action of the coagulation system by thrombin. In addition hirudin is a potent inhibitor of the thrombin mediated platelet aggregation. At present this compound is investigated both in the treatment and prevention of venous and arterial thromboembolic diseases in experimental

https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00003
An integrative analytical approach was employed in a study published in the British Journal of Pharmacology by Yan Sun and et al. to clarify the anticoagulant effects of C-terminus-modified hirudins, HV1 and hirudin variant 2 of Hirudinaria manillensis (HM2). In umbrella sampling of the changes in the Gibbs free energy in the molecular system when the C-terminus of hirudin was pulled away from

https://www.merriam-webster.com/medical
Medical Dictionary. Search medical terms and abbreviations with the most up-to-date and comprehensive medical dictionary from the reference experts at Merriam-Webster. Master today's medical vocabulary. Become an informed health-care consumer!

https://www.definitions.net/definition/hirudin%20therapy
Meaning of hirudin therapy. What does hirudin therapy mean? Information and translations of hirudin therapy in the most comprehensive dictionary definitions resource on the web. ... Definitions for hirudin therapy hirudin ther·a·py This dictionary definitions page includes all the possible meanings, ... Medicinal leech populations were

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717768/
The concept of Unani medicine is based on balancing body humours, the imbalance of which causes diseases. The application of leech therapy in medical and dental science is well recognized. Although easy and non-invasive, complications also exist. The article aims to presents a brief review on the applications of leech therapy.

https://connects.catalyst.harvard.edu/Profiles/profile/1225837
Hirudin Therapy. "Hirudin Therapy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Use of HIRUDINS as an anticoagulant in the treatment of cardiological and

https://www.utmedicalcenter.org/treatments/hyperbaric-oxygen-therapy
Hyperbaric Oxygen Therapy (HBO) is a medical treatment that increases the amount of oxygen in the patient's blood, allowing oxygen to pass more easily through the plasma into the wounds to heal them. HBO chambers surround patients with 100% oxygen at higher than normal atmospheric pressures.

https://www.utmedicalcenter.org/locations/hardin-valley-clinic
About Us. Our team at Hardin Valley uses a range of therapeutic exercises, equipment and procedures to improve muscle strength, range of motion, posture, balance and coordination. The team at Hardin Valley enjoys helping their patients reach their potential and empowering them to continue to live an active and healthy lifestyle.

https://www.utmedicalcenter.org/treatments/speech-language-pathology
Cognitive and Language Therapy for Acquired Communication Disorders, ex. stroke, trauma, or progressive neurological disorders; ... The University of Tennessee Medical Center provides medical treatment without regard to race, age, color, national origin, ethnicity, culture, language, socioeconomic status, religion, sex, gender identity, gender

https://www.utmedicalcenter.org/treatments/cognitive-behavioral-therapy-insomnia-cbt-i
If you have any questions, please call our office at: 865-305-8761. The Cognitive Behavioral Therapy Program consists of 8 weekly sessions of 30-60 minutes. You will meet with a Sleep Therapist (coach) at the UT Sleep Disorders Center. The program will provide you with the skills to improve your sleep and to maintain this improvement with time.