https://www.youtube.com/watch?v=pwIjcGBgB_s
How to administer Newcastle Disease Vaccine is a must watch video for you if you must learn the only right way to do chicken vaccination. Disease prevention

https://www.drugs.com/vet/newcastle-disease-vaccine-b1-type-lasota-strain.html
This vaccine contains the B1 type, LaSota strain of Newcastle disease virus. It is recommended for the initial vaccination of healthy chickens at one day of age using the eyedrop method, or for the vaccination of healthy chickens 14 days of age or older using the drinking water or coarse aerosol spray as an aid in the prevention of Newcastle

https://www.zoetisus.com/content/_assets/docs/Poultry/Newcastle-Disease-Vaccine-B1-Type-LaSota-Strain-Product-Profile.pdf
y layer, breeder or broiler chickens 2 weeks of age or older.For spray administration, this vaccine is recommended for the revaccination of heal. y layer, breeder or broile. eeks of age or older.Dosage: one dose per bird.INDICATIONSNewcastle Disease Vaccine, B1 Type, LaSota Strain, is recommended for administration.

https://www.youtube.com/watch?v=LMpVKDlvhGg
How to administer Lasota Vaccine on Chicks / Vaccination against New Castle Disease.A Simple and Straight Forward Step-by-step Guide to help you administer L

https://www.zoetisus.com/products/poultry/newcastle-lasota
Newcastle Lasota is a monovalent live virus vaccine for the immunization of chickens against Newcastle disease. Indications Newcastle Disease Vaccine, B1 Type, LaSota Strain, has been shown to be effective for the vaccination of healthy chickens 1 day, 2 weeks or 4 weeks of age and older against Newcastle Disease. Available as.

https://www.drugs.com/vet/newcastle-disease-vaccine-b1-type-lasota-strain-live-virus.html
These Newcastle Disease Vaccines may be used for the revaccination of healthy chickens 4 weeks of age or older by spraying the vaccine solution above the chickens. A sprayer that delivers a coarse spray quickly and evenly is recommended. 1. Remove seal from a vial of vaccine. 2.

https://www.merckvetmanual.com/poultry/newcastle-disease-and-other-paramyxovirusinfections/newcastle-disease-in-poultry
Newcastle disease is a severe, systemic, and fatal viral disease of poultry due to virulent strains of avian paramyxovirus type 1. Clinical signs in unvaccinated birds include sudden death, lethargy, and respiratory distress. Diagnosis is based on laboratory confirmation. Vaccines prevent clinical signs but not infection, and the control of the

https://www.thepoultrysite.com/articles/newcastle-disease-how-to-control-the-disease-and-reduce-post-vaccine-reactions
To analyse the protection of the vaccine and the reaction, it is important to understand a few points: The method of vaccination: Ideally, the best method of vaccination for Newcastle vaccines are spray or eye drop. It is very important to check the size of the droplets, as fine drops can cause reactions. The ideal droplet size is between 160

https://www.drugs.com/vet/newcastle-bronchitis-vaccine-b1-type-lasota-strain-mass-type-holland-strain.html
3. Fill vaccine container with cool, distilled water. 4. Pour reconstituted vaccine into a clean container and add 5 ounces (150 mL) of cool water for each 1,000 chickens to be vaccinated. 5. Place the vaccine solution into spray canister and walk through the house spraying at the rate of 1,000 chickens per minute.

https://www.cdc.gov/vaccines/hcp/admin/administer-vaccines.html
Each vaccine has a recommended administration route and site. This information is included in the manufacturer's package insert for each vaccine. Deviation from the recommended route may reduce vaccine efficacy or increase local adverse reactions. Health care personnel should always perform hand hygiene before administering vaccines by any route.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701384/
Inactivated vaccines are administered individually via a parenteral route such as intramuscular or subcutaneous (s.c.) injection, making the process time consuming and labour intensive. These vaccines mainly induce high, long-lasting humoral immunity, whereas they are poor inducers of cellular or mucosal immune responses.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532065/
The IgA antibody concentrations of chickens immunized intranasally with the LaSota live vaccine or orally with NDV-CS-NPs increased quickly and peaked at week 4 post immunization. After four weeks, chickens immunized with the LaSota live vaccine had a sharp decline in IgA antibody concentrations compared with those in the NDV-CS-NPs group.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131810/
3. Newcastle disease vaccines. There are three main goals when using vaccination to help control ND: i) decrease or eliminate clinical disease; ii) decrease the amount of virulent virus shed; and iii) increase the infectious dose of the challenge virus ( Kapczynski et al., 2013 ).

https://www.youtube.com/watch?v=ibR8Cs9OZ_Q
Giving NCD LASOTA vaccine to our 1week old RIR chicks

https://www.thepoultrysite.com/articles/newcastle-disease-key-points-about-vaccination
Live vaccines, some points are important: the strain, related to the pressure of infection in the area. For example, in medium to high-risk areas, the use of a cloned LaSota strain is beneficial, because it will deliver the highly effective strain, namely the LaSota strain without the disadvantage of this strain, that is reactivity.

https://www.fao.org/4/ac802e/ac802e04.htm
There are two basic processes used to produce a thermostable Newcastle disease vaccine. 1. Isolation of naturally occurring thermostable variants of the virus. 2. Increasing the thermostability of this variant by artificial selection in the laboratory. A seed lot system is used to produce the vaccine.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565102/
Over the years, LaSota, B1 and other genotype II-based live attenuated vaccines have been used to curtail the menace of NDV in the global poultry industry (Kapczynski, Afonso & Miller 2013). However, the vaccines have frequently been associated with the severe post-vaccinal respiratory reactions that may predispose the birds to secondary

https://pubmed.ncbi.nlm.nih.gov/29211892/
Newcastle disease remains a major concern to the poultry industry; however, it can be managed with effective vaccination programs. The main objective of this study was to evaluate the effect of 2 1× doses of live LaSota strain Newcastle disease virus (NDV) vaccine administered oculo-nasally on d one and 21 on development of humoral and cell-mediated immune response in broilers, and to compare

https://pubmed.ncbi.nlm.nih.gov/1179399/
An intramuscular N.D.C. vaccination with LaSota vaccine, in animals of less than ten weeks which were previously vaccinated by the spray method at about 5 days and 25 days against N.C.D., leads to an immunity of at least three months, as expressed by a high concentration of haemagglutination inhibiting antibodies in the circulatory system.

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0053314
Background Newcastle disease (ND) is a highly contagious viral disease of poultry caused by pathogenic strains of the Newcastle disease virus (NDV). Live NDV vaccines are administered by drinking water, eyedrops or coarse aerosol spray. To further enhance mucosal immune responses, chitosan nanoparticles were developed for the mucosal delivery of a live NDV vaccine. Methodology/Principal

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080498/
However, systemic assessment has rarely been performed to observe the changes of the NDV-attenuated vaccine LaSota strain with contamination and its role in exogenous virus infection. Using FAdV and CIAV isolated from the abovementioned vaccine , contaminated vaccines and corresponding virus PBS diluent were artificially prepared as trial

https://pubmed.ncbi.nlm.nih.gov/37030151/
In this study, after vaccination with the most widely used LaSota vaccine (genotype II), chickens with different hemagglutination inhibition (HI) antibody levels were challenged with heterologous virulent NDV strains of genotypes VII and IX to evaluate how antibody levels relate to clinical protection and infection or virus shedding. Under the

https://www.drugs.com/vet/newcastle-disease-vaccine-b1-type-b1-strain.html
B1 Type, B1 Strain, Live Virus. This vaccine contains the B1 type, B1 strain of Newcastle disease virus. It is recommended for the initial vaccination of healthy chickens at one day of age using the eyedrop or coarse spray method, or for the vaccination of healthy chickens 14 days of age or older using the drinking water or coarse aerosol spray