https://www.nature.com/articles/s41580-024-00748-6
The development of high-throughput RNA structure profiling methods in the past decade has greatly facilitated our ability to map and characterize different aspects of RNA structures transcriptome

https://www.nature.com/articles/d41586-019-02554-z
None of this stopped Watson and Crick from speculating about how the components of the DNA molecule — the four nucleotide bases adenine, guanine, thymine and cytosine, connected to a backbone of

https://www.nature.com/articles/s41589-021-00805-7
RNA molecules fold into complex structures that enable their diverse functions in cells. Recent revolutionary innovations in transcriptome-wide RNA structural probing of living cells have ushered

https://www.sciencedaily.com/releases/2021/07/210722113007.htm
The findings, published in a new study in the journal Molecular Cell, also reveal that the process of DNA being copied into RNA -- transcription -- indirectly shapes the architecture of the genome

https://www.pnas.org/doi/10.1073/pnas.2112677119
Recent events have pushed RNA research into the spotlight. Continued discoveries of RNA with unexpected diverse functions in healthy and diseased cells, such as the role of RNA as both the source and countermeasure to a severe acute respiratory syndrome coronavirus 2 infection, are igniting a new passion for understanding this functionally and structurally versatile molecule.

https://pubmed.ncbi.nlm.nih.gov/25903461/
The information encoded by DNA is both digital - the precise base specifying, for example, amino acid sequences - and analogue. The latter determines the sequence-dependent physicochemical properties of DNA, for example, its stiffness and susceptibility to strand separation. Most importantly, DNA chirality enables the formation of supercoiling

https://www.pnas.org/doi/pdf/10.1073/pnas.2112677119
Now more than ever our community should strive to think and talk about RNA struc-ture in a way that reflects its true behavior. Doing so has practical bene ts: For example, Moderna scientists showed. the importance of mRNA structure for stability and thus ef cacy of the RNA at the heart of their vaccine (1).

https://www.youtube.com/watch?v=nuC1_jiqq5g
DNA Nanoswitches are a super cool tool that can detect RNA-based viruses, including the novel coronavirus (SARS-CoV-2). DNA Nanoswitches take advantage of th

https://scitechdaily.com/new-discovery-shows-human-cells-can-write-rna-sequences-into-dna-challenges-central-principle-in-biology/
In a discovery that challenges long-held dogma in biology, researchers show that mammalian cells can convert RNA sequences back into DNA, a feat more common in viruses than eukaryotic cells. Cells contain machinery that duplicates DNA into a new set that goes into a newly formed cell. That same c

https://pubmed.ncbi.nlm.nih.gov/36359677/
DNA's structure is dynamic and has the ability to adopt a variety of structural conformations in addition to its most widely known double-stranded DNA (dsDNA) helix structure. Stability and structural dynamics of dsDNA play an important role in molecular biology. In vivo, DNA molecules are folded in a tightly confined space, such as a cell

https://www.sciencedaily.com/releases/2024/05/240501125755.htm
May 4, 2020 — New research shows that the ability to extinguish fearful memories relies on a change in DNA structure: from Z-DNA to B-DNA. The findings suggest that the more easily you can

https://www.nature.com/subjects/dna-and-rna
A molecular jack-of-all-trades. DNA is much more than the genetic information it carries. It is a versatile material for creating systems with tailor-made functionalities that are having an

https://www.jbc.org/article/S0021-9258(20)46684-0/fulltext
The first is methodologies we developed for chemically synthesizing DNA and RNA. Synthetic DNA and RNA continue to be an essential research tool for biologists, biochemists, and molecular biologists. The second is developing new approaches for solving important biological problems using synthetic DNA, RNA, and their analogs.

https://www.khanacademy.org/science/biology/dna-as-the-genetic-material/structure-of-dna/a/nucleic-acids
As stated in the summary at the end of the article, DNA and RNA have different functions. While DNA stores genetic information, RNA is involved in protein synthesis and gene regulation, as well as storing genetic information in some viruses. DNA and RNA also have different structures; DNA's phosphate-sugar backbone contains deoxyribose, while

https://www.sciencedaily.com/releases/2021/08/210812123103.htm
The experimental DNA stack system constitutes proof-of principle that a polymerising DNA chemistry can be used as a dynamic data structure to store two types of DNA signal in a last-in first-out

https://www.khanacademy.org/science/what-are-living-things-made-of/xf9343b6caff766ff:the-molecular-basis-of-inheritance/xf9343b6caff766ff:structure-of-dna-and-rna/v/dna-deoxyribonucleic-acid
DNA. DNA, or deoxyribonucleic acid, is the molecular basis for inheritance, discovered in the mid-1800s and understood in 1953 with the double helix structure. Composed of a sugar-phosphate backbone and base pairs (adenine-thymine, guanine-cytosine), DNA stores genetic information, replicates, and expresses traits.

https://www.nature.com/articles/nrg3681
RNA molecules influence all steps of gene expression and regulation 1.Once thought to be only a cellular messenger between DNA and proteins, RNA is now known to be involved in many aspects of

https://www.ncbi.nlm.nih.gov/books/NBK538241/
The remarkable structure of deoxyribonucleic acid (DNA), from the nucleotide up to the chromosome, plays a crucial role in its biological function. The ability of DNA to function as the material through which genetic information is stored and transmitted is a direct result of its elegant structure. In their seminal 1953 paper, Watson and Crick unveiled two aspects of DNA structure: pairing the

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107331/
Abstract. DNA and RNA are remarkable because they can both encode information and possess desired properties, including the ability to bind specific targets or catalyze specific reactions. Nucleotide modifications that do not interfere with enzymatic synthesis are now being used to bestow DNA or RNA with properties that further increase their

https://sciencenotes.org/dna-vs-rna-similarities-and-differences/
Three differences between DNA and RNA are that DNA uses the base thymine while RNA uses uracil, DNA uses the sugar deoxyribose while RNA uses ribose, and usually DNA is double-stranded and RNA is single-stranded. (image: Sponk, Creative Commons 3.0) DNA (deoxyribonucleic acid) and RNA (ribonucleic acid) are the two types of nucleic acids found

https://www.nature.com/subjects/dna
DNA (deoxyribonucleic acid) is the nucleic acid polymer that forms the genetic code for a cell or virus. Most DNA molecules consist of two polymers (double-stranded) of four nucleotides that each

https://phys.org/news/2024-06-scientists-generation-dna-wide-range.html
A research group led by Dr. Edward Curtis has developed two new types of catalytic DNA molecules (deoxyribozymes) that can reveal the presence of target molecules through fluorescence or color.

https://www.sciencedaily.com/releases/2024/06/240621122917.htm
Researchers have uncovered how specific DNA rearrangements called inverted triplications contribute to the development of various genetic diseases. The study reveals that during DNA repair

https://www.science.org/doi/10.1126/science.ado3867
Recent studies attempting to model DNA repair in the context of replication have yielded somewhat contradictory conclusions as to whether a nick needs to be converted to a DSB to trigger HR (17, 22, 23).It was also noted that replication fork collision with a nick on the lagging strand appears to stimulate HR more strongly and is more dependent on BRCA1 for repair accuracy than a leading

https://www.nature.com/articles/s41525-023-00387-4.pdf
RNA primer Overview of RNA, RMPs, and their mechanisms of action. RNA is a biomolecular class with a broad array of biological functions and represents a rapidly growing category of drugs with the

https://www.nature.com/subjects/dna-replication
DNA replication is the biological process by which an exact copy of a deoxyribonucleic acid (DNA) molecule is created and it is the basis for biological inheritance. Each of the two strands of the