https://www.ehlers-danlos.com/what-is-eds/vascular-ehlers-danlos-syndrome-veds/
The complications of vEDS can be life-threatening and include aneurysm, dissection, and rupture of the arteries and rupture of organs. vEDS may also cause a variety of other symptoms, including extensive bruising and spontaneous pneumothorax. ... Diagnosis, natural history, and management in vascular Ehlers-Danlos syndrome . Vascular Ehlers

https://www.jvascsurg.org/article/S0741-5214(16)30876-X/fulltext
Vascular Ehlers-Danlos syndrome (EDS) is a relatively rare genetic syndrome that occurs owing to disorders in the metabolism of fibrillary collagen. These defects affect the soft connective tissues resulting in abnormalities in the skin, joints, hollow organs, and blood vessels. Patients with these defects frequently present at a young age with spontaneous arterial complications involving the

https://thevedsmovement.org/veds/what-are-the-signs/
Some signs of VEDS are easy to see. Every person's experience with Vascular Ehlers-Danlos syndrome is slightly different. Some may have every feature, some may have only a few features, and other people have different combinations of features. Some people may not have outward signs at all. Some signs of VEDS are easier to see than others

https://thevedsmovement.org/wp-content/uploads/2023/01/VEDS-FactSheet-2023-English.pdf
Vascular Ehlers-Danlos syndrome (VEDS) is a concern because of potentially life-threatening complications. ... diagnosis have had a significant complication, such as bowel rupture, arterial rupture, or spontaneous pneumothorax. Some of those with VEDS may develop a prematurely aged appearance, especially

https://thevedsmovement.org/veds/how-is-the-body-affected/
The following are symptoms found in people with Vascular Ehlers-Danlos Syndrome (VEDS): Cardiovascular and arterial characteristics . There is no increased risk of valvular or structural cardiac defects. There is an increased risk of coronary artery dissection, and as a result, myocardial infarction (heart attack).

https://www.ahajournals.org/doi/10.1161/CIRCGENETICS.114.000507
Vascular Ehlers-Danlos syndrome (vEDS) is an autosomal dominant disease that affects the arteries, bowels, uterus, and skin. Affected individuals can have spontaneous rupture of hollow organs, such as the bowels or gravid uterus, along with arterial dissections and ruptures that lead to premature death. The arterial disease seen in

https://www.ncbi.nlm.nih.gov/sites/books/NBK1494/
Vascular Ehlers-Danlos syndrome (vEDS) is characterized by arterial, intestinal, and/or uterine fragility; thin, translucent skin; easy bruising; characteristic facial appearance (thin vermilion of the lips, micrognathia, narrow nose, prominent eyes); and an aged appearance to the extremities, particularly the hands. Vascular dissection or rupture, gastrointestinal perforation, or organ

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573967/
Introduction. The Ehlers-Danlos syndromes (EDS) are a group of 13 heritable disorders characterized by three common features: tissue fragility, skin hyperextensibility, and joint hypermobility ().Vascular Ehlers-Danlos syndrome (vEDS, OMIM #130050), one of the EDS subtypes, is a rare and severe inherited connective tissue disorder (CTD) with a prevalence estimated at 1/50 000.

https://my.clevelandclinic.org/health/diseases/22696-vascular-ehlers-danlos-syndrome
The most common symptoms of vascular Ehlers-Danlos syndrome include: Skin differences. People with this condition have thinner, translucent and delicate skin (making veins very visible). Certain areas of skin will also age faster than others, especially skin on your hands and feet. Distinctive facial features.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11079293/
Introduction. Ehlers-Danlos syndrome (EDS) refers to a group of autosomal dominant genetic disorders affecting connective tissues, which consists of more than 13 subtypes based on the new EDS classification 1.The vascular EDS (vEDS) subtype is a dominantly inherited disorder secondary to pathogenic variants within the COL3A1gene encoding type III collagen chains 2.

https://www.nature.com/articles/s41431-023-01343-7
The UK National Diagnostic Service for Ehlers-Danlos Syndromes (EDS) was established in 2009 for the rare types of EDS. Vascular EDS (vEDS) is an inherited connective tissue disorder caused by

https://pubmed.ncbi.nlm.nih.gov/27687326/
Abstract. Background: Vascular Ehlers-Danlos syndrome (EDS) is a relatively rare genetic syndrome that occurs owing to disorders in the metabolism of fibrillary collagen. These defects affect the soft connective tissues resulting in abnormalities in the skin, joints, hollow organs, and blood vessels. Patients with these defects frequently

https://www.ehlers-danlos.org/information/vascular-ehlers-danlos-syndrome/
This information is intended for people who have been recently diagnosed with vascular Ehlers-Danlos syndrome (vEDS) and their friends and relatives. ... tissues and blood vessels makes this much more difficult for the surgeon and puts you at an increased risk of serious complications. Of course in a life threatening situation, surgery may be

https://pubmed.ncbi.nlm.nih.gov/22143279/
The Ehlers-Danlos syndrome consists of a group of inherited connective tissue disorders caused by defects in the synthesis of collagen. The vascular type 4 form of Ehlers-Danlos syndrome (VEDS) is associated with serious vascular complications in young adults, such as the spontaneous rupture of large-caliber and medium-caliber arteries, often without true aneurysm formation or dissection.

https://thevedsmovement.org/veds/what-is-veds/
Vascular Ehlers-Danlos syndrome (VEDS) is a genetic condition that makes the arteries and hollow organs prone to tear, due to a mutation in the COL3A1 gene. ... By age 20, about a quarter of those with a known VEDS diagnosis have had a significant complication, such as bowel rupture, arterial rupture, or spontaneous pneumothorax.

https://ehlers-danlos.org.nz/veds/
Diagnosis of Vascular Ehlers-Danlos Syndrome. In many people without a family history of the condition a diagnosis of vascular EDS is not considered until they present with a medical emergency such as dissection or rupture of an artery, an organ rupture (for example bowel or womb) or after the discovery of one or more aneurysms (a swelling in an artery).

https://www.ahajournals.org/doi/pdf/10.1161/CIRCGENETICS.114.000507
Vascular Ehlers-Danlos syndrome (vEDS) is an autosomal dominant disease that affects the arteries, bowels, uterus, and skin. Affected individuals can have spontaneous rupture of hollow organs, such as the bowels or gravid uterus, along with arterial dissections and ruptures that lead to premature death. The arterial disease seen in

https://www.jacc.org/doi/10.1016/j.jacc.2019.01.058
Vascular Ehlers-Danlos syndrome (vEDS) is a rare genetic connective tissue disorder secondary to pathogenic variants within the COL3A1 gene, resulting in exceptional arterial and organ fragility and premature death. The only published clinical trial to date demonstrated the benefit of celiprolol on arterial morbimortality.

https://marfan.org/wp-content/uploads/2021/04/VEDS-Fact-Sheet.pdf
Vascular Ehlers-Danlos syndrome (vEDS) is an inherited condition that is quite variable. People are often diagnosed when they have easy and frequent bruising that is not explained by other causes, a spontaneous bowel, or arterial tears, or because other family members are affected. Some people have characteristic facial features, thin skin, and

https://pubmed.ncbi.nlm.nih.gov/30793832/
Vascular Ehlers-Danlos syndrome (vEDS) is a connective tissue disorder due to defective type III collagen production and is associated with arterial rupture, spontaneous intestinal perforation, and gravid uterine rupture. ... The temporal relation of pulmonary manifestations to arterial and intestinal complications in vEDS has not been well

https://www.researchgate.net/publication/380134210_Editorial_Ehlers-Danlos_syndrome_from_bedside_to_bench
Background: Vascular-type Ehlers-Danlos syndrome (vEDS) is caused by collagen III deficit resulting from heterogeneous mutations in COL3A1, which occasionally causes sudden death due to arterial

https://thevedsmovement.org/what-to-expect/diagnosis/
VEDS should be suspected in individuals with any one of the major features below or several minor features, particularly in those younger than age 40 years. The major features are: Family history of Vascular Ehlers-Danlos syndrome; Arterial rupture at a young age; Intestinal rupture in the absence of known diverticular disease or other bowel issues

https://www.msn.com/en-us/health/medical/signs-and-symptoms-of-ehlers-danlos-syndrome/ar-AA1llvVJ
Vascular Ehlers-Danlos syndrome (vEDS) is a serious form of EDS that causes fragile blood vessels that are more prone to tearing and rupturing, which can be life-threatening.

https://www.msn.com/en-us/health/medical/understanding-ehlers-danlos-syndromes/ss-AAX6uDE
Vascular Ehlers-Danlos syndrome (vEDS) The third most common type of the condition, vascular Ehlers-Danlos syndrome (vEDS) weakens blood vessels and makes your organs more likely to have a tear.

https://thevedsmovement.org/2021/03/23/fibromuscular-dysplasia-and-vascular-ehlers-danlos/
The carotid and renal findings of Vascular Ehlers-Danlos syndrome can appear similar to the most common type of fibromuscular dysplasia, known as multifocal fibromuscular dysplasia. VEDS should be included in the differential diagnosis for patients with FMD. The presence of multiple aneurysms and/or tears (dissections) in arteries in addition