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Altering Serotonin Levels Changes Monkey Behavior and Status [Show ID: 12680]Explore More Science & Technology on UCTV(https://www.uctv.tv/science)Science an

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799948/
RESULTS. We first asked whether low serotonin levels influenced monkeys' preferences as revealed by a simple risky decision-making task in which monkeys prefer the risky option when choices with equal expected values are presented rapidly (every 1-3 s) (McCoy and Platt, 2005; Hayden and Platt, 2007 ). Based on prior results, we held the

https://www.nature.com/articles/s41386-022-01433-y
The neurotransmitter serotonin (5-HT) is important in establishing dominance hierarchies in various species. For example, direct modulation of 5-HT signaling in monkeys changes their dominance

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084567/
Serotonin (5-hydroxytryptamine, 5-HT) is acknowledged as a major neuromodulator of nervous systems in both invertebrates and vertebrates. It has been proposed for several decades that it impacts animal cognition and behavior. In spite of a completely distinct organization of the 5-HT systems across the animal kingdom, several lines of evidence

https://www.ulm.edu/~palmer/TheBiochemistryofStatusandtheFunctionofMoodStates.htm
McGuire and Raleigh (1975) demonstrated that serotonin level covaries with changes of status in vervet monkeys. Moreover, artificially raising the serotonin levels in subordinate vervet monkeys with fluoxetine (Prozac) results in these individuals rising in status, in some cases to alpha rank (Raleigh, 1991).

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Altering Serotonin Levels Changes Monkey Behavior and Status. 5 minutes. Altering Serotonin Levels Changes Monkey Behavior and Status (#12680) EMBED. Like what you learn? Donate to UCTV to support informative & inspiring programming. DONATE. Related Programs

https://academic.oup.com/jeb/article/31/8/1180/7381980
Abstract. Traits that undergo massive natural selection pressure, with multiple events of positive selection, are hard to find. Social behaviour, in social animals, is crucial for survival, and genetic networks involved in behaviour, such as those of serotonin (5‐HT) and other neurotransmitters, must be the target of natural selection.

https://pubmed.ncbi.nlm.nih.gov/19553236/
Moreover, lowering brain serotonin function significantly decreased the premium required for monkeys to switch their preference to the risky option, suggesting that diminished serotonin signaling enhances the relative subjective value of the risky option. These results implicate serotonin in risk-sensitive decision making and, further, suggest

https://link.springer.com/content/pdf/10.1007/978-94-009-3359-0_13.pdf
of drugs altering serotonin function and aggressive behaviour. Findings are largely ... WHOLE BLOOD SEROTONIN 1. (Vervet monkeys): levels higher in dominant than in subordinate males (Raleigh et a1. 1984) ... 4. (Humans): levels higher in high-status males compared to lower status males (McGuire et al. 1983b) 5. (Humans): levels higher in males

https://psychologyrocks.org/wp-content/uploads/2019/12/raleigh1984.pdf
The relationship between blood and brain serotonin levels has yet to be fully specified. Under some conditions, changes inblood serotonin levels parallel changes brain serotonin levels. For example, both are similarly affected by pharmacologie interventions that augment precursor avail¬ ability (eg, tryptophan loading5,6), that inhibit

https://pubmed.ncbi.nlm.nih.gov/6703857/
We examined the effects of spontaneous and induced changes in social status, temporary isolation from the social group, and membership in single male groups on whole-blood serotonin concentrations. We found that in male vervet monkeys, elevated blood serotonin concentration is a state-dependent consequence of active occupation of the dominant

https://www.sciencedirect.com/science/article/pii/0162309584900062
This paper reviews findings from studies of physiological-behavioral relationships in captive male vervet monkeys (Cercopithecus aethiops sabaeus).Among dominant males whole blood serotonin levels exceed levels for subordinate males; social status changes are accompanied by changes in whole blood serotonin and basal cortisol levels; and animals of different social status behave differently in

https://www.nature.com/articles/s41593-022-01213-3
Although we understand how serotonin receptors function at the single-cell level, what role different serotonin receptors play in regulating brain-wide activity and, in turn, human behavior

https://academic.oup.com/scan/article/4/4/346/1668148
We first asked whether low serotonin levels influenced monkeys' preferences as revealed by a simple risky decision-making task in which monkeys prefer the risky option when choices with equal expected values are presented rapidly (every 1-3 s) (McCoy and Platt, 2005; Hayden and Platt, 2007). Based on prior results, we held the inter-trial

https://www.thedodo.com/serotonin-in-monkeys-we-can-le-494428086.html
Published on April 2, 2014 at 4:42 PM. A monkey's serotonin -- the molecule that plays a role in happiness -- flows when he one-ups a fellow monkey. We'd rather imagine our primate ancestors living in social harmony, but understanding their conflict helps us make sense of our neurochemical ups and downs. Every mammal has the same core brain

https://www.sciencedirect.com/science/article/abs/pii/0014488680900898
The behavioral effects of altering serotonin neurotransmission by chronic drug treatments in socially living vervet monkeys (Cercopithecus aethiops sabaeus) were examined.Animals received tryptophan (TRP, 20 mg/kg/day), parachlorophenylalanine (PCPA, 80 mg/kg/day), 5-hydroxytryptophan (5-HTP, 40 mg/kg/day), chlorgyline (10 mg/kg/day), or PCPA followed by concurrent PCPA and 5-HTP.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853349/
Abstract. Brain monoamines, and serotonin in particular, have repeatedly been shown to be linked to different psychiatric conditions such as depression, anxiety, antisocial behaviour, and dependence. Many studies have implicated genetic variability in the genes encoding monoamine oxidase A (MAOA) and the serotonin transporter (5HTT) in

https://www.nature.com/articles/s41398-020-00880-9
Serotonin is involved in a wide range of mental capacities essential for navigating the social world, including emotion and impulse control. Much recent work on serotonin and social functioning

https://onlinelibrary.wiley.com/doi/full/10.1111/jeb.13295
In cases in which a range was informed for lifespan, average values were computed. In addition, when specific data for a species were unavailable, or the current domesticated status of the species was considered to interfere in behaviour, the value for an extant wild species of the genus was used (Fig. 1, and Table S2). For qualitative traits

https://neuro.psychiatryonline.org/doi/full/10.1176/jnp.15.3.294
In one study, female monkeys with higher levels of serotonin were more likely to attain a high social dominance ranking within their social group than females with below average CSF 5-HIAA. 15 The impact of serotonin on aggression and social status was systematically analyzed in a set of experiments on vervet monkeys 78 that involved the

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817523/
Figure 1. Serotonin shapes moral judgments. (A) Relative to placebo and the noradrenaline reuptake inhibitor atomoxetine, the serotonin reuptake inhibitor citalopram made subjects less likely to endorse harming one person to save many others, specifically when harms were emotionally salient. (B) The effects of citalopram on moral judgdment were

https://nyaspubs.onlinelibrary.wiley.com/doi/full/10.1111/nyas.12229
Several studies have investigated the relationship between serotonin function and responder behavior in the UG. Emmanuele et al. 69 reported that platelet serotonin levels were inversely correlated with responders' rejection rates. However, given that serotonin does not penetrate the blood-brain barrier, plasma levels may not correspond to

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310545/
This has been highlighted by increased use of SSRI antidepressants to treat maternal depression during pregnancy, which has raised critical and yet unanswered questions about the impact of altering 5-HT levels in utero and the implications for subsequent behavior and mental health (Gaspar et al., 2003; Homberg et al., 2010; Homberg and Lesch