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Biochemistry | Cytochrome P450 Catalytic Cycle
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27,836 Views • Aug 20, 2014 • Click to toggle off description
Welcome to Catalyst University! I am Kevin Tokoph, PT, DPT, and this is one of my earlier biochemistry videos where we discuss the catalytic cycle of the enzyme, cytochrome P450.

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Views : 27,836
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Date of upload: Aug 20, 2014 ^^


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YouTube Comments - 21 Comments

Top Comments of this video!! :3

@twoHRdrive

3 years ago

For the homolytic bond cleavage of the oxygen molecule, I am a little confused. What exactly is setting off the homolytic cleavage in the first place? I get that one electron from the O-O double bond goes to one O atom, and the other electron to the other O atom. And I understand that Fe II donates an electron to one of the oxygens. But why does this cleavage of one of the molecular oxygen bonds happen? Any explanation would be immensely helpful! Thank you!

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@FizzlGrizzL

7 years ago

you just blew my mind what a great video bro <3

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@NereticSC2

9 years ago

If you want to get rid of the circle blinking up every time you touch down with your pen  - just look at the windows configuration for mouse and pen - with your configuration it always trys to do a right click.

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@SharonCabanu

6 years ago

Thank you very much! Such a nice explanation!

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@joelpaz1929

7 years ago

Thanks! Really helpful!

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@gautamkannan1909

4 years ago

You just drew a piece of art!!!

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@twoHRdrive

5 years ago

Sorry for the silly question, but could you please explain how the heme iron reached an oxidation state of 3+ while chelated to the four nitrogens and the one sulfur? Hope to hear from you soon! :) Thanks!

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@natalia9509

2 years ago

Stupid question: my teacher said the sixth bond is initially with a H2O molecule. Is it because in that position it is exposed to an aqueous environment and therefore tends to bind the water molecule or is there another more specific (and correct) reason? Thank you for your videos, always extremely helpful! :)

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@ashleyives6872

7 years ago

At 5:30, why are you using singlet oxygen? Thanks for the videos BTW, they're very helpful!

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@vaishnaviramakrishna265

4 years ago

You have a new subscriber 🙋.. thanks for the good teaching!

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@pasqualegarruto3256

3 years ago

grazie infinite!!!!! you best!

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@kameshranjan3938

6 years ago

Verry helpful...

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@SpaceAndStarsGalore

4 years ago

You’re amazing !

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@Saruno1297

4 years ago

❤️

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@RunForFunFun

7 years ago

Just curious. Isn't Ionic bond stronger than covalen bond? It seems you are saying covalent is stronger than the ionic

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