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Misha Bharti, a 42-year-old housewife, walked into the hospital with an unimaginable problem — blackened, gangrenous fingers. There was no injury, no diabetes, and no circulation disorder. The mystery deepened until doctors discovered the shocking cause — a prescribed migraine medication: ergotamine.

Ergotamine, commonly used to treat severe migraines, works by narrowing blood vessels. But in some individuals, especially with prolonged use or overdose, it can cut off blood supply to the limbs, leading to peripheral vascular ischemia and even gangrene.

Misha had unknowingly risked her limbs to fight headaches.

She’s not alone. Other drugs with similar vascular risks include:

Nicotine patches

Cocaine

Amphetamines

Beta-blockers in patients with peripheral vascular disease

Vasopressin

⚠️ If you notice numbness, cold hands, or skin color changes while on medication — seek medical help immediately. Not all side effects are mild — some are life-altering.

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