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Manu Uncle is an Indian Malayalam-language comedy-drama film directed by Dennis Joseph and produced by Joy Thomas. Starring Mammootty, M. G. Soman, Prathapachandran, Lissy, and B. Thyagarajan. Mohanlal made a cameo appearance as himself. The film was theatrically released on 7 April 1988 and was a box office success, completing a 100-day run in theatres. The movie was filmed in Kollam. The film won a National Award for Best Children's Film. Suresh Gopi also appeared in a cameo role, playing the character S.I Minnal Prathapan. The character eventually developed a cult following several years after the release of the film.

Manu is a Kollam based researcher in astronomy. Manu's father is a police officer. Ravunni, an exporter, is their family friend. Antony and Mary are neighbours of Manu. Their children are Dany a.k.a. Lother and Ikru. Manu's elder sister's children come from Delhi for their vacation. They are accompanied by Dany and Ikru which make up a four-member team headed by Dany.

The children happen to visit the Art Museum on the very same time when Marthanda Varma's Crown is stolen. Ikru noticed the robbers, Gomez, Appu and Kittu but was not able to describe them to his Grandpa. Manu, who has a well-equipped communication system, is able to listen to a conversation between Kittu and Gomez planning to loot Marthanda Varma's Sword. Manu informs his father about the plan, and they both rush to Padmanabhapuram Palace. Gomez, meanwhile already gets hold of the sword and while escaping the palace encounters Manu and his father. A fight follows in which Manu is injured by Gomez; now Manu's father is in pursuit of the robbers alone. But the robbers kill Manu's father in a planned lorry accident. The viewers are just now able to figure out the mastermind behind the robbery is; Ravunni, the family friend. Unfortunately for him though, the incident was witnessed by Khader, a young orphan who happened to be in that lorry. The robbers try to catch the boy, but the boy manages to escape from them and in the process ends up meeting the four children, and tells them that their Grandpa was not dead in an accident but was killed.

Directed by Dennis Joseph
Screenplay by Shibu Chakravarthy
Story by Dennis Joseph
Produced by Joy Thomas
Starring: Mammootty, Mohanlal, Suresh Gopi, M. G. Soman, Prathapachandran, Lissy,B. Thyagarajan
Cinematography: Jayanan Vincent
Edited by K. Shankunny
Music by Shyam
Production company: Jubilee Productions

Mammootty as Manu, an aspiring scientist
Kuriyan Chakko as Dany a.k.a. Lother
Amit as Ikru
Anoop C. Parameswaran as Shanku
Sonia as Renu
Sandeep as Khader
Lissy as Uma, Manu's Sister
M. G. Soman as DYSP, Manu's Father
Prathapachandran as Ravunni, Manu's Family Friend
R. Thyagarajan as Gomez, Ravunni's Partner
K. P. A. C. Azeez as Antony, Dany's and Ikru's Father
K. P. A. C. Lalitha as Mary, Dany's and Ikru's Mother
Murali Menon as Kittu
Mohan Jose as Security Guard at Ravunni's house
Jalaja as Manu's Elder Sister
Mohanlal as Himself (cameo appearance)
Suresh Gopi as SI 'Minnal' Prathapan (cameo Appearance)

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