Molecular Biophysics - Lecture 08 concepts
22 videos • 8,289 views • by Erik Lindahl
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Lecture 08, concept 01: The main component of a membrane is a lipid bilayer
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Lecture 08, concept 02: Lipids are amphiphatic, often zwitterions, and aggregate into bilayers
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Lecture 08, concept 03: The internal structure of the lipid bilayer
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Lecture 08, concept 04: The fluid mosaic model of cellular membranes
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Lecture 08, concept 05: Membrane proteins were crystallized by solubilisation in detergent
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Lecture 08, concept 06: The first membrane protein structure - bacteriorhodopsin
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Lecture 08, concept 07: Interactions between membrane proteins and lipids
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Lecture 08, concept 08: Membrane proteins insert through the translocon
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Lecture 08, concept 09: Membrane protein helix packing & the GXXXG motif
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Lecture 08, concept 10: Membrane protein topology - the von Heijne "positive inside" rule
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Lecture 08, concept 11: Membrane transport - passive vs. active & non-mediated vs. mediated
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Lecture 08, concept 12: Ion channels
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Lecture 08, concept 13: The KcsA bacterial K+ ion channel
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Lecture 08, concept 14: The Kv voltage-gated K+ ion channel(s) in vertebrates
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Lecture 08, concept 15: The aquaporin water channel
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Lecture 08, concept 16: Ligand-gated ion channels mediate signals in the nervous system
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Lecture 08, concept 17: The NKA (Na/K ATPase) pump maintains the ion imbalance by using ATP
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Lecture 08, concept 18: Signaling - G-protein coupled receptors (GPCRs)
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Lecture 08, concept 19: Signaling - Receptor Tyrosine Kinases (RTKs)
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Lecture 08, concept 20: Viral fusion membrane proteins
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Lecture 08, concept 21: Lipid Nanoparticles (LNPs) for mRNA vaccine delivery
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Lecture 08: Study questions
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