Genomics2Proteins Portal
11 videos • 1,233 views • by Broad Institute The Genomics 2 Proteins (G2P) portal is a discovery tool to link genetic screening outputs to protein sequence and structure, offering two major capabilities: Visualization of human genetic variations from databases such gnomAD, ClinVar, and HGMD and protein sequence annotation (features, e.g. domains, ligand-binding pockets, active sites) from UniProt database, pre-mapped on protein sequences and structures. Interactive and automated mapping of variations, protein features, and readouts from functional genomic assays (e.g., saturation mutagenesis) on protein sequences and structures. This playlist is dedicated to tutorials and case studies on how to use the portal for different applications.