Alcohol Metabolism
5 videos • 76 views • by Dr Bijoya Chatterjee High NADPH conc in cytosol and mitochondria during Ethanol metabolism are produced. This causes changes in various metabolic pathways Fatty acid and triacylglycerol synthesis Increases but their transport from liver is inhibited so there is fat accumulation in liver. Chronic consumption of ethyl alcohol causes hepatic steatosis and steatohepatitis due to accumulation of fat in liver. Both these conditions are reversible. However if chronic alcohol consumption contnues the liver undergoes fibrosis and cirrhosis. This may result in hepatis carcinoma in some.